Program
Timetable
Distinguished Lecture 1
November 29 (Wed.) 13:50-14:50 Room A (5F Big Hall)
Variability of drug metabolism due to (epi)genetic and (patho)physiological factors - the struggle for better prediction
- Chairs: Hiroshi Yamazaki Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University
- Miki Nakajima Faculty of Pharmaceutical Sciences, Kanazawa University
- Speaker: Ulrich M. Zanger Molecular and Cell Biology, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany
Distinguished Lecture 2
November 30 (Thu.) 13:00-14:00 Room A (5F Big Hall)
Establishing the Selectivity of Organic Cation Transporters: Grappling with Inconvenient Truths
- Chair: Mikihisa Takano Graduate School of Biomedical & Health Sciences, Hiroshima University
- Carsten Ehrhardt School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin
- Speaker: Stephen H. Wright Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ
President's Lecture
November 30 (Thu.) 15:30-16:00 Room A (5F Big Hall)
Message from the JSSX President: Current topics in drug metabolism and pharmacokinetics and clinical pharmacotherapy
- Chair: Mikihisa Takano Graduate School of Biomedical & Health Sciences, Hiroshima University
- Speaker: Hiroshi Yamazaki Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University
Symposium 1
November 29 (Wed.) 9:30-11:30 Room A (5F Big Hall)
Recent topics of interface of between "Drug Metabolism and Pharmacokinetics" and "Toxicology"
- Organizer: Miki Nakajima Faculty of Pharmaceutical Sciences, Kanazawa University
- Chairs: Kousei Ito Graduate School of Pharmaceutical Sciences, Chiba University
- Yoichi Naritomi Analysis & Pharmacokinetics Research Labs., Astellas Pharma Inc.
- "Strategic Drug Design to Eliminate Metabolic Activation of Hapatotoxic Drugs"
- Speaker: Tomoyuki Ohe Faculty of Pharmacy, Keio University
- "Application of cytochrome P450 reactivity assessment to liver toxicity prediction"
- Speaker: Takamitsu Sasaki Depertment of Molecular Toxicology, School of Phrmaceutical Sciences, University of Shizuoka
- "Bile acid dependent hepatocytes toxicity - beyond BSEP inhibition by parent drug"
- Speakers: Kousei Ito Graduate School of Pharmaceutical Sciences, Chiba University
- "Assessment of drug-induced hepatotoxicity, considering drug metabolism, using 3-D hepatocyte cultures and chimeric mice with humanized liver"
- Speaker: Seigo Sanoh Graduate School of Biomedical and Health Sciences, Hiroshima University
Symposium 2
November 29 (Wed.) 9:30-11:30 Room B (5F Small Hall)
Roles of Pharmacokinetic Studies on Cell Therapeutics
- Organizer: Takashi Kuwabara Department of Clinical Pharmacy, Yokohama University of Pharmacy
- Chairs: Makiya Nishikawa Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science
- Masataka Oitate Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd.
- "Biodistribution evaluation in "MEASURE", the Multisite Evaluation Study on Analytical Methods for Non-clinical Safety Assessment of Human-derived Regenerative Medical Products"
- Speaker: Masahiro Yahata Preclinical Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd.
- "Biodistribution study of human mesenchymal stem cells in mice using ARLG, IVIS, and qPCR"
- Speaker: Takahiro Nakamura Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd.
- "Cell-based therapy with high safety through manipulating the in vivo fate of transplanted cells"
- Speaker: Kosuke Kusamori Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science
- "Cell-injection therapy for the treatment of corneal endothelial dysfunction"
- Speaker: Noriko Koizumi Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University
Symposium 3
November 29 (Wed.) 9:30-11:30 Room C (2F Tougen-Fukuju)
From academic research to clinic based on cooperation between industry, government and academia
- Organizers / Chairs: Hideyoshi Harashima Faculty of Pharmaceutical Sciences Laboratory for Molecular Design of Pharmaceutics, Hokkaido University
- Yoshinobu Takakura Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University
- "Drug discovery Innovation for nonstandard peptides"
- Speaker: Hiroaki Suga Department of Chemistry, Graduate School of Science, The University of Tokyo
- "Model-based Population Pharmacokinetic Analysis and Exposure-Response Analysis of Nivolumab"
- Speaker: Tomoya Ohno ONO Pharmaceutical CO., LTD., Translational Medicine Center, Clinical Pharmacology
- "Viewpoint on Assessment of Healthcare Technologies"
- Speaker: Yoshihide Esaki Ministry of Economy, Trade and Industry
- "Challenge to improve probability of drug discovery and streamline clinical development cost"
- Speaker: Kazuhiko Mori Ministry of Health, Labour and Welfare
Symposium 4
November 29 (Wed.) 15:00-17:00 Room A (5F Big Hall)
QSP in oncology - practical application, challenge and opportunity -
- Organizers: Masayo Oishi Clinical pharmacology, Pfizer Japan Inc.
- Koji Chiba Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy.
- Chairs: Hiroto Hatakeyama Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
- Naomi Nagai Department of Pharmaceutical Sciences, Musashino University
- "Systems-based understanding of mechanisms underlying the adverse reactions with kinase inhibitors"
- Speaker: Masashi Honma Department of Pharmacy, the University of Tokyo Hospital
- Chairs: Yuko Mori Clinical pharmacology, Pfizer Japan Inc.
- Yasuhisa Nagasaka Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.
- "QSP Models in Preclinical Oncology Drug Discovery"
- Speaker: Mary E. Spilker Translational Modeling and Simulation, Medicine Design, Pfizer Worldwide Research and Development
- Chairs: Teruki Hamada Drug Disposition & Analysis, Research Division, Axcelead Drug Discovery Partners, Inc.
- Noriko Okudaira Clinical Pharmacology Department, R&D Division, Daiichi Sankyo Co., Ltd.
- "An Integrated Mechanistic Model to Characterize Efficacy and Toxicity of Antibody Drug Conjugates"
- Speaker: Andy Zhu Modeling and Simulation, Department of Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge MA USA.
- Chairs: Ryosei Kawai Clinical Science Japan, Bayer Yakuhin, Ltd.
- Takayo Ueno Clinical Pharmacology Strategy, Bristol-Myers Squibb K.K.
- "Using mechanistic physiological models to enhance oncology research and drug development"
- Speaker: Michael Reed Rosa & Co., LLC, USA
Symposium 5
November 29 (Wed.) 15:00-17:00 Room B (5F Small Hall)
Imaging Technologies: Emerging Modality for Drug Development and PD/Tox Marker Discovery
- Organizer: Akio Kawamura Pharmacokinetics & Toxicology Laboratories, Senju Pharmaceutical Co., Ltd.
- Organizer / Chair: Nobuaki Watanabe Drug Metabolism & Pharmacokinetics Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd.
- Chair: Hidefumi Kaji Advanced Medical Business Development Department, Drug Development Service Segment, LSI Medience Corporation
- "Introduction of our symposium"
- Speaker: Akio Kawamura Pharmacokinetics & Toxicology Laboratories, Senju Pharmaceutical Co., Ltd.
- "PET Imaging in Drug Development"
- Speaker: Akihiro Noda Bioimaging, Analysis & Pharmacokinetics Research Labs., Drug Discovery Research, Astellas Pharma Inc.
- "Optical imaging in vivo: IVIS & MSOT"
- Speaker: Rira Watanabe Biomarker Department, R&D Division, Daiichi Sankyo Co., Ltd.
- "Potentialities of application of MALDI mass spectrometry imaging to pharmacokinetics studies"
- Speaker: Masanobu Nishidate Clinical Bioanalytics Group Translational Clinical Research Science & Strategy Dept., Chugai Pharmaceutical Co., Ltd.
- "Distribution Analysis of Epertinib in Brain Metastasis of HER2-positive Breast Cancer by Imaging Mass Spectrometry and Prospect for Antitumor Activity"
- Speaker: Yukari Tanaka Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, SHIONOGI & CO., LTD.
Symposium 6
November 29 (Wed.) 15:00-17:25 Room C (2F Tougen-Fukuju)
How we can apply the metabolomics data to find biomarkers for the drug effect?
- Organizer / Chair: Hiroyuki Kusuhara Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- Chair: Tappei Takada Department of Pharmacy, the University of Tokyo Hospital
- "Contribution of DMPK Researchers to Biomarker Research in Drug Development"
- Speaker: Noriko Okudaira Clinical Pharmacology Department, R&D Division, Daiichi Sankyo Co., Ltd.
- "Advanced lipidomics to identify the functional metabolites of omega-3 polyunsaturated fatty acids"
- Speaker: Makoto Arita Division of Physiological Chemistry and Metabolism, Keio University Faculty of Pharmacy / RIKEN-IMS
- "Chrono-omics analysis for exploring diagnostic and therapeutic targets of neuropathic pain"
- Speaker: Satoru Koyanagi Faculty of Pharmaceutical Sciences, Kyushu University
- "Biomarker Research for Drug-Induced Liver Injury in Rats"
- Speaker: Makoto Yamazaki DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation
- "Utilization of a large-scale metabolome reference for analysis of drug metabolism"
- Speaker: Daisuke Saigusa Tohoku Medical Megabank Organization / School of Medicine, Tohoku University
- "Screening of Endogenous Substrates of SLC22A4 by Metabolomic Approach Based on Transporting Activity and Substrate Recognition"
- Speaker: Yusuke Masuo Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
- "Early Risk Assessment for hepatic OATP-mediated Drug Interactions by Evaluation of Endogenous Substrates"
- Speaker: Issey Takehara Biomarker Department, R&D Division, Daiichi Sankyo Co., Ltd.
Symposium 7
November 30 (Thu.) 9:30-11:30 Room A (5F Big Hall)
Expansion of the field of transporter research ~Transporter meets new fields~
- Organizer: Ikumi Tamai Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
- Chairs: Masahiro Okuda Department of Pharmacy, Mie University Hospital
- Kazuya Maeda Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- "Lysosome-resident amino acid/oligopeptide transporter, SLC15A4, as a therapeutic target for systemic lupus erythematosus"
- Speaker: Noriko Sorimachi Department of Molecular Immunology and Inflammation, Research Institute National Center for Global Health and Medicine
- "Impact of interplay between facilitated diffusion and metabolism on intracellular accumulation of purine nucleobases and their analogues"
- Speaker: Katsuhisa Inoue Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
- "Transporter meets hepatitis viruses"
- Speaker: Koichi Watashi Department of Virology II, National Institute of Infectious Diseases
- "Synthetic Molecules for Detecting and Eliminating Human Pluripotent Stem Cells"
- Speaker: Motonari Uesugi Institute for Chemical Research, Kyoto University
Symposium 8
November 30 (Thu.) 9:30-11:30 Room C (2F Tougen-Fukuju)
Investigations of physiological function of metabolizing enzymes and applications to drug discovery
- Organizer: Miki Nakajima Faculty of Pharmaceutical Sciences, Kanazawa University
- Chairs: Seigo Sanoh Graduate School of Biomedical and Health Sciences, Hiroshima University
- Tetsuya Nakagawa Preclinical Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd.
- "Inflammation- and disease-associated regulation of drug-metabolizing enzymes in the liver"
- Speaker: Kouichi Yoshinari Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
- "Physiological functions of xenobiotic-metabolizing CYP3A enzymes"
- Speaker: Kaoru Kobayashi Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
- "Cytochrome P450 involved in biotransformation of both endogenous and xenobiotic substances"
- Speaker: Takanori Hashizume Laboratory of Drug Metabolism & Pharmacokinetics, Faculty of Pharmacy, Osaka Ohtani University
- "Metabolism and physiological function of exogenous and endogenous substances by drug-oxidizing enzymes"
- Speaker: Hiroshi Yamazaki Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University
- "Pathophysiological function of human CYP2J2 in cancer and its inhibitors influencing potential antitumor effects"
- Speaker: Satoshi Yamaori Department of Pharmacy, Shinshu University Hospital
Symposium 9
December 1(Fri.)9:30-12:00 Room A (5F Big Hall)
New drug treatments and the precision medicine for cancer therapy
- Organizer: Ichiro Ieiri Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University
- Chairs: Satohiro Masuda Department of Pharmacy, Kyushu University Hospital
- Hitoshi Ishizuka Daiichi Sankyo Co., Ltd.
- "Lung cancer therapy targeted against driver gene alterations: Clinical evidence and translational research"
- Speaker: Tetsuya Mitsudomi Thoracic Surgery, Faculty of Medicine, Kindai University
- "Modelling of population pharmacokinetics (PK) and pharmacodynamics (PD) of antibody-drug conjugates (ADC): a case study of DS-8201a, a novel HER2-targeting ADC"
- Speaker: Kazutaka Yoshihara Clinical Pharmacology Department, R&D Division, Daiichi Sankyo Co., Ltd.
- "Clinical advantages of a nanoparticle albumin-bound paclitaxel (ABRAXANE®)"
- Speaker: Ikuo Yamamiya Pharmacokinetics Research Laboratories, TAIHO Pharmaceutical Co. Ltd.
- "Molecular targeting anti-tumor drug development of ALK inhibitor, alectinib; Key features contributed the precision medicine for cancer therapy"
- Speaker: Hisakazu Katsuki Translational Clinical Research Science & Strategy Dept., Chugai Pharmaceutical Co., Ltd.
- Title : unfixed
- Speaker: Shigehisa Kitano National Cancer Center Hospital
Symposium 10
December 1(Fri.)9:30-12:00 Room B (5F Small Hall)
New horizon of microphysiological system (in vitro) technology oriented to prediction of human pharmacokinetic "Prediction of biliary excretion clearance"
- Organizer / Chair: Shuichi Sekine Laboratory of Biopharmaceutics, Graduate school of Pharmaceutical Sciences, Chiba University
- Chair: Kenji Tabata Analysis & Pharmacokinetics Research Labs., Institute for Drug Discovery Research, Astellas Pharma. Inc.
- "Expectations for microphysiological systems of the liver in the assessment of drug metabolism, transport, and toxicity in drug discovery"
- Speaker: Kazuhiro Tetsuka Analysis & Pharmacokinetics Research Labs., Astellas Pharma Inc.
- "Two-dimensional Culture System of Human Hepatocytes for in vitro ADMET Studies using Hepatocytes Isolated from Chimeric Mice with Humanized Livers"
- Speaker: Chise Tateno-Mukaidani Research and Development Department, PhoenixBio Co., Ltd.
- "An approach to the construction of three-dimensional hepatic tissues using a microfluidic device"
- Speaker: Ryo Sudo Department of System Design Engineering, Faculty of Science and Technology, Keio University
- "Construction of In Vitro MPS Technology Based on 3D-Blood Capillary Models"
- Speaker: Michiya Matsusaki Department of Applied Chemistry, Graduate School of Engineering, Osaka University
- "Generation of functional hepatocytes from human pluripotent stem cells for pharmaceutical research"
- Speaker: Hiroyuki Mizuguchi Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University
Symposium 11
December 1(Fri.)9:30-12:00 Room D(2F Heian)
Development of oligonucleotide pharmaceuticals promoted by pharmacokinetics
- Organizer / Chair: Takashi Kuwabara Department of Clinical Pharmacy, Yokohama University of Pharmacy
- Chair: Hiroshi Kodaira Kyowa Hakko Kirin Co., Ltd., R&D Division, Research Functions Unit, Research Core Function Laboratories
- "Current status of research & development of Nucleic acid Therapeutics"
- Speaker: Makoto Koizumi Modality Research Laboratories, Biologics Division, Daiichi Sankyo Co., Ltd.
- "New Paradime of treatment for Spinal Muscular Atrophy with Antisense oligonucleotide therapy, Nusinersen - its mode of action and clinical applications -"
- Speaker: Shinichi Torii Biogen Japan Ltd.
- "Development of antisense drug targeting PCSK9"
- Speaker: Mariko Harada-Shiba Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute
- "Muscular delivery of siRNA by Conjugation of Anti-CD71 Fab' Fragment"
- Speaker: Kenichi Miyata Innovative Biology Laboratories, Takeda Pharmaceutical Company Limited
- "Exosomes: Naturally occurring vesicles for nucleic acid delivery"
- Speaker: Yusuke Yoshioka Division of Molecular and Cellular Medicine, National Cancer Center Research Institute
Symposium 12
December 1(Fri.)14:00-16:30 Room A (5F Big Hall)
Recent regulatory topics for DMPK researchers
- Organizer: Yoshiro Saito Division of Medicinal Safety Science, National Institute of Health Sciences
- Chairs: Shinichi Ninomiya Drug Development Solutions Division, Pharma & Research Business, Sekisui Medical Co., LTD.
- Nobuaki Watanabe Drug Metabolism & Pharmacokinetics Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd.
- "Guideline on population pharmacokinetic and pharmacodynamic and recent trends population pharmacokinetic and pharmacodynamic analysis in regulatory review"
- Speaker: Yoshinori Ochiai Advanced Review with Electronic Data Promotion Group/Office of New Drug I, Pharmaceuticals and Medical Devices Agency
- "Revision of ICH S5 Guideline"
- Speaker: Kazushige Maki Office of New Drug III, Pharmaceuticals and Medical Devices Agency
- Drafting the "Questions and Answers" for the ICH S9 guideline, "Nonclinical Evaluation for Anticancer Pharmaceuticals"
- Speaker: Dai Nakae Laboratory of Food Safety Assessment Science, Department of Nutritional Science and Food Safety, Faculty of Applied Biosciences, Tokyo University of Agriculture
- "ICH S11 Nonclinical Safety Testing in Support of Development of Pediatric Medicines"
- Speaker: Yuhji Taquahashi Division of Cellular and Molecular Toxicology, Biological Safety Research Center, National Institute of Health Sciences
- "ICH M9: Biopharmaceutics Classification System-based Biowaivers"
- Speaker: Ryosuke Kuribayashi Office of Generic drugs, Pharmaceuticals and Medical Devices Agency
- "ICH M10: Guideline on Bioanalytical Method Validation"
- Speaker: Akiko Ishii-Watabe Division of Biological Chemistry and Biologicals, National Institute of Health Sciences
- "Accelerating regulatory science initiative"
- Speaker: Yoshiro Saito Division of Medicinal Safety Science, National Institute of Health Sciences
Symposium 13
December 1(Fri.)14:00-16:30 Room B (5F Small Hall)
How to elucidate the metabolism of new chemical entities
- Organizer: Miki Nakajima Faculty of Pharmaceutical Sciences, Kanazawa University
- Chairs: Kaoru Kobayashi Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
- Shin-ichi Inoue Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd.
- "Human Intestinal Raf Kinase Inhibitor Protein (RKIP) Catalyzes Prasugrel as a Bioactivation Hydrolase"
- Speaker: Miho Kazui Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd.
- "Aldehyde oxidase mediated drug metabolism and basic approaches in drug discovery"
- Speaker: Tomoyuki Isobe Tokyo New Drug Research Laboratories, Kowa Co., Ltd.
- "Identification of sulfotransferase and methyltransferase isozymes responsible for the metabolism of peficitinib, a Janus kinase inhibitor"
- Speaker: Kazuo Oda Analysis & Pharmacokinetics Research Laboratories, Drug Discovery Research, Astellas Pharma Inc.
- "Dipeptidyl peptidase-4 greatly contributes to the cyano group hydrolysis of vildagliptin in human liver"
- Speaker: Mitsutoshi Asakura Department of Pharmacy, Shinshu University Hospital
- "Roles of hydrolases and aldehyde oxidase in controlling of pharmacokinetics and drug toxicity"
- Speaker: Tatsuki Fukami Faculty of Pharmaceutical Sciences, Kanazawa University
Symposium 14
December 1(Fri.)14:00-16:30 Room C (2F Tougen-Fukuju)
Invitation to Pharmacometrics
- Organizer: Akihiro Hisaka Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
- Chair: Takahiko Tanigawa Clinical Sciences Japan, Bayer Yakuhin, Ltd.
- "Start Pharmacometrics from Pharmacokinetics"
- Speaker: Koji Chiba Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy
- Chair: Koji Chiba Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy
- "Pharmacometrics for clinical development of New drug –Rivaroxaban as an example–"
- Speaker: Takahiko Tanigawa Clinical Sciences Japan, Bayer Yakuhin, Ltd.
- Chair: Hiroyuki Yoshitsugu Clinical Research Area, Japan Development, MSDK.K.
- "MID3 (Model-Informed Drug Discovery and Development)"
- Speaker: Akiyuki Suzuki Pharmacometrics Group, Clinical pharmacology, Pfizer Japan Inc.
- Chair: Fumiyoshi Yamashita Graduate School of Pharmaceutical Sciences, Kyoto University
- "Clinical research that is feasible for scientists in academia: model-based meta-analysis (MBMA)"
- Speaker: Akihiro Hisaka Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
Round table discussion
- "Science and communication skills necessary for pharmacometrics research"
- Modulators: Atsunori Kaibara
Clinical Pharmacology, Astellas Pharma Inc. - Modulators: So Miyoshi
Clinical pharmacology, Pfizer Japan Inc.
JSSX-KSAP Joint Symposium
November 30 (Thu.) 9:30-11:30 Room B (5F Small Hall)
Drug-induced organ toxicity -Mechanism, Prediction, and Prevention-
- Organizer / Chair from JSSX: Kousei Ito
Graduate School of Pharmaceutical Sciences, Chiba University - Organizer / Chair from KSAP: Young-Jin Chun
College of Pharmacy and Center for Metareceptome Research, Chung-Ang University, Korea
- "Keratinocytes can predict risk for developing drug-induced liver toxicity in individuals"
- Speaker: Ryoichi Fujiwara School of Pharmacy, Kitasato University
- "Determination of sleep deprivation-induced brain toxicity by multi-platform mass spectrometry"
- Speaker: Sung Won Kwon College of Pharmacy, Seoul National University, Korea
- "Reconstitution of drug hypersensitivity reaction in HLA-transgenic mice model"
- Speaker: Kousei Ito Graduate School of Pharmaceutical Sciences, Chiba University
- "Roles of Annexin A5 in Mitochondria-Dependent Apoptosis Induced by Various Anticancer Drugs"
- Speaker: Young-Jin Chun College of Pharmacy and Center for Metareceptome Research, Chung-Ang University, Korea
Basic Course
December 1(Fri.)9:30-12:00 Room C (2F Tougen-Fukuju)
Basic course of pharmacokinetics related to drug development
- Organizers / Chairs: Hiroyuki Kusuhara Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- Motohiro Kato Drug Metabolism and Pharmacokinetics Research Labs., Chugai Pharmaceutical Co., LTD.
- "Basic Pharmacokinetics, which you can not ask about even now.
-Illustrated study guide for effectively utilizing Pharmacokinetics-" - Lecturers: Hideki Hirabayashi Takeda Pharmaceutical Company Limited
- "Basics of PK/PD analysis -Model selection and parameter estimation-"
- Lecturers: Tatsuhiko Tachibana Pre-clinical Research Department, Chugai Pharmaceutical Co., LTD.
3rd Predoctoral Symposium for Front-Line Scientists
November 30 (Thu.) 15:00-17:30 Room E(2F Zuiun)
Pharmacokinetic research for leading the future medicine
- Organizers: Daichi Onozato Graduate School of Pharmaceutical Sciences, Nagoya City University
- Ayako Tokunaga Graduate School of Biomedical Sciences, Nagasaki University
- Kaori Miyazaki Graduate School of Pharmaceutical Sciences, Tokyo University of Pharmacy and Life Sciences
- Chair: Yoshihisa Mimura Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University
- "A New Mechanism of Drug-Beverage Interaction: Effect of Solution Osmolality on Luminal Water Volume and Drug Absorption in Intestine"
- Speaker: Kazuki Ichijo Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
- Chair: Masaki Takahashi Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
- "Development of a novel differentiation method of human induced pluripotent stem cell-derived enterocytes"
- Speaker: Tomoki Kabeya Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University
- Chair: Hiromasa Aoki Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University
- "Distribution of doxorubicin in the embryo after administration to the mother"
- Speaker: Satoshi Kitaoka Department of Clinical pharmacokinetics, Graduate School of Pharmaceutical Sciences, Hoshi University
- Chair: Yu Takahashi Division of Pharmaceutics, Graduate School of Pharmaceutical Sciences, Keio University
- "Design and evaluation of long-acting thioredoxin by using albumin fusion technology as a therapeutic agent for acute kidney injury and its crosstalk with other organs"
- Speaker: Kento Nishida Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University
- Chair: Hiroki Kamioka Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare
- "Substrate specificities of UDP-glucuronosyltransferase in rats and mice: comparison with human UGT isoforms"
- Speaker: Hiroki Oki Laboratory of Molecular Life Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University
- Chair: Daichi Onozato Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University
- "Development of a novel alveolar epithelial cell model and its application to the study on drug-induced epithelial-mesenchymal transition"
- Speaker: Junya Deguchi Department of Pharmaceutics and Therapeutics, Graduate school of Biomedical & Health Sciences, Hiroshima University
Education Lecture
- Chairs: Ayako Tokunaga Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University
- Kaori Miyazaki Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
- "Studies on drug fostering, pharmaceutical technology, drug discovery based on biological clock"
- Speaker: Naoya Matsunaga Department of Glocal Healthcare, Graduate School of Pharmaceutical Science, Kyushu University